
I have not shared this with many people, not even the people I work with daily. I was chosen, about 6 months ago to be involved in the first stages of a research project having to do with development of a new screening tool to assess adverse effects of atypical antipsychotic medications (AAPM) in elderly nursing home patients. I am very excited to be involved with this project as the tool may be used in every long term care facility in the nation to assess all nursing home residents using these medications and the side effects they may be exhibiting.
A little background, I hope it doesn't bore you to tears.
The current tool used is called the AIMS (Abnormal Involuntary Movement Scale.) This scale was developed when traditional antipsychotic medications like haloperidol (Haldol), fluphenazine, and thioridiazine were the primary medications of choice. These older medications can cause many long term side effects.
The older antipsychotic medications were not very forgiving. They cause tardive dyskinesia a long term side effect which includes rhythmic involuntary movement of the tongue, lips, or jaw, protrusion of the tongue, puckering of the mouth, flailing movements or involuntary movements of the extremities. There are more severe side effects such as acute spasm of muscle groups, fixed upper gaze, pseudo parkinsonism (ridged, slow movement, tremor, and pill-rolling) and akathisia a form of agitation manifested by the inability to sit still, pacing, or tapping feet. All these things were caused by the older antipsychotic medications. In a nut shell the people put on the medications in the 50's and 60's are in the nursing home system now. They display these side effects, some more blaring than others...my observation, it's like they have a form of cerebral palsy and antsy pants all rolled into one. They use several calories just sitting because they are always in motion. Once they have these side effects they can not be reversed.

The newer antipsychotic drugs such as clozopine, Zyprexa, risperidone, aripiprazole, and ziprasidone are called atypical antipsychotic medications (AAPM)are defined as being less likely to produce these long term side effects. The incidents of tardive dyskinesia appears to be 1/5 with these second-generation antipsychotics. But with these drugs, may come metabolic side affects like diabetes II, abnormal lipid profiles, and hyperprolactinemia. There is also speculation they may cause orthostatic hypotension.
The AIMS test which is currently used is a 24 step test, 12 observation steps then answer 12 questions on the bottom from 0-4, none (0) to severe (4) side effects noted.
The new test, which is in the works, will be a 10 step examination, including orthostatic blood pressure (laying, then sitting, then standing). We will also be gathering baseline blood sugars on all participants. I will be gathering data in my role in the research. I'm so excited to be a part of it, as I hope before I retire I will be using this very tool to assess my residents. That would be so cool!!

Just under 2 million Americans live in nursing homes; the lifetime risk of spending at least some time in a nursing facility is 43%. At least 50% of all nursing home residents have cognitive impairment, and mental disorders are estimated to affect 75 to 90% of the nursing home population. The prevalence of psychotic drug use in long-term care facilities ranges from 33-90%. Accusations about excessive use of antipsychotic medications in nursing homes have been raised suggesting they were being used for staff convenience without appropriate diagnosis and side effect monitoring.
Where I work currently we are the medication police. Every 60 days the residents I care for are evaluated by their physician and we review the need for these medications or try, slowly, to eliminate them or reduce the dosage. As for staff convenience, I could see this being a problem if you look at the whole picture. My opinion is these medications are useful, and needed. People suffering from dementia do not want to feel anxious, paranoid, angry, lash out...it's about their comfort, not mine. There is a need for these medications even with the risk of side effects mentioned above. It's about quality of life, comfort, and making through another day.